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Cialis (or tadalafil) for one and a half days suppresses the production of the enzyme PDE5 in the body, causing the cessation of erection. The drug is a selective PDE5 inhibitor. What does it mean? Cialis is more actively blocking the PDE5 enzyme, leaving the rest of the useful PDE enzymes alone. For example, PDE3 is involved in cardiac muscle contraction. And the effect of Cialis on this enzyme is 10 thousand times weaker than on PDE5. 700 times weaker, it acts on another useful enzyme PDE6, found in the retina and responsible for the correct color rendition. Therefore, if you simultaneously take 700 tablets of Cialis, then for 36 hours there will be difficulties with the recognition of blue and green colors, and if 10 thousand tablets – disruptions in the work of the heart may begin.
Nevertheless, a kind of Viagra for women has already been developed and is undergoing clinical trials. The first tablets for women should appear approximately in a couple of years.
The most traumatic psychological factor in men is sexual disorders. Among all the options: a decrease in libido, disturbances of arousal, a disorder in the quality of erections and the onset of orgasm – it is a violation of erection that leads to the most serious psychological trauma, including suicide attempts. Modern medicine considers the potency as a necessary condition for a normal quality of life. That is, without a normal erection, there can be no talk of psychological health.
The main causes of erectile dysfunction are various vascular diseases, diabetes, lack of testosterone and trauma. Over 152 million men suffer from this disease in the world, and, according to statistics, more than 50 percent of men over the age of 40 are at risk of losing potency.
There are many ways to treat this disorder. For example, injections right into the penis shortly before sexual activity, increasing blood flow to the penis. This radical method is quite effective, but over time, men practicing it against the background of pain in the penis after injections begin to develop a neurotic fear of sex life.
There are drugs that are in the form of balls are introduced into the penis to increase erection. Vacuum therapy has been known since the days of ancient China – blood is retained in the penis with the help of a ring at the base. If all of the above does not help, then only the surgical method remains: a special implant is inserted into the penis, which is inflated with a pear-pump when it becomes necessary to have sexual intercourse. Against all these horrors, tablets with inhibitors look fantastic. No wonder the magazine Time called the drug Cialis invention of the year.